pymetrozine

Basic information

  • Product Name:pymetrozine
  • CasNo.:123312-89-0
  • MF:C10H11N5O

Physical and Chemical Properties

  • Purity:99%
  • Melting Point:217oC
  • Appearance:colorless crystals
Inquiry

Product Details

CasNo: 123312-89-0

MF: C10H11N5O

Appearance: colorless crystals

Factory Export Top Purity pymetrozine 123312-89-0 In Stock

  • Molecular Formula:C10H11N5O
  • Molecular Weight:217.23
  • Appearance/Colour:colorless crystals 
  • Vapor Pressure:0Pa at 25.03℃ 
  • Melting Point:217oC 
  • Refractive Index:1.665 
  • PKA:12.90±0.40(Predicted) 
  • Flash Point:>230 °C 
  • PSA:69.95000 
  • Density:1.33 g/cm3 
  • LogP:0.51890 

Pymetrozine(Cas 123312-89-0) Usage

Descriptioin

Pymetrozine is a new neuroactive insecticide. It has a remarkable selectivity for sucking insect pests, such as aphids, whiteflies, and plant hoppers, due to its systemic action. Pymetrozine is the only representative of the pyridine azomethines, a new class of insecticides. Pymetrozine has been determined to be of low acute toxicity to humans, birds, aquatic organisms, mammals, and bees. It is also not mutagenic.

Uses

Pymetrozine is a systemic insecticide used in agriculture to control many pests, including aphids, whiteflies, and other sucking insects:

Aphids: Pymetrozine is effective against many strains of aphids on potatoes, leafy vegetables, and other brassica crops

Whiteflies: Pymetrozine can reduce whiteflies on ornamental plants in greenhouses

Other sucking insects: Pymetrozine is effective against all life stages of sucking insects, including planthoppers and leafhoppers

Definition

ChEBI: A member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2H)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4.

InChI:InChI=1/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+

123312-89-0 Relevant articles

An efficient protocol for the production of pymetrozine via a new synthetic strategy

Zhou, Qifan,Du, Fangyu,Shi, Yajie,Liu, Wenqiang,Liu, Dongdong,Chen, Guoliang

, p. 434 - 438 (2018/09/12)

A practical four-step synthesis of pymet...

Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine

European Food Safety Authority

European Food Safety Authority (EFSA), Parma, Italy

The conclusions were reached on the basis of the evaluation of the representative uses of pymetrozine as an insecticide on tomato, aubergine, potato and oilseed rape. The reliable endpoints concluded as being appropriate for use in regulatory risk assessment, derived from the available studies and literature in the dossier peer reviewed, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified.

The insecticide pymetrozine selectively affects chordotonal mechanoreceptors

Jessica Ausborn, Harald Wolf, Wolfgang Mader, Hartmut Kayser

J Exp Biol (2005) 208 (23): 4451–4466.

Pymetrozine is a neuroactive insecticide but its site of action in the nervous system is unknown. Based on previous studies of symptoms in the locust, the feedback loop controlling the femur–tibia joint of the middle leg was chosen to examine possible targets of the insecticide.

Supramolecular water morphology and methanol solvate in a functionalized pymetrozine host

Wang,Xu,Cheng,Shao,Li

experimental part, p. 2541 - 2545 (2012/08/27)

The crystals of functionalized pymetrozi...

123312-89-0 Process route

methyl (E)-1- (2-oxopropyl)-2-(pyridin-3-ylmethylene)hydrazine-1-carboxylate

methyl (E)-1- (2-oxopropyl)-2-(pyridin-3-ylmethylene)hydrazine-1-carboxylate

C<sub>11</sub>H<sub>15</sub>N<sub>5</sub>O<sub>2</sub>

C11H15N5O2

pymetrozine
123312-89-0

pymetrozine

hydrazone of pyridine-3-carboxaldehyde
26364-02-3

hydrazone of pyridine-3-carboxaldehyde

1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene
13362-77-1

1,4-bis(3-pyridyl)-2,3-diaza-1,3-butadiene

Conditions
Conditions Yield
With hydrazine hydrate; In ethanol; at 25 ℃;
37%
28%
15%
14%
With hydrazine hydrate; In ethanol; at 80 ℃; Solvent;
16%
36%
18%
21%
With hydrazine hydrate; In ethanol; at 80 ℃;
15%
35%
19%
17%
With hydrazine hydrate; In ethanol; at 50 ℃;
21%
24%
10%
8%
C<sub>10</sub>H<sub>12</sub>ClN<sub>5</sub>O

C10H12ClN5O

pymetrozine
123312-89-0

pymetrozine

Conditions
Conditions Yield
With potassium carbonate; In methanol; at 25 - 30 ℃; for 5h; Reagent/catalyst;
85%

123312-89-0 Upstream products

  • 500-22-1
    500-22-1

    3-pyridinecarboxaldehyde

  • 123313-07-5
    123313-07-5

    2,3,4,5-tetrahydro-3-oxo-4-amino-6-methyl-1,2,4-triazine

123312-89-0 Downstream products

  • 1834-93-1
    1834-93-1

    pyridine-3-carbaldehyde-(2,4-dinitro-phenylhydrazone)

  • 123313-07-5
    123313-07-5

    2,3,4,5-tetrahydro-3-oxo-4-amino-6-methyl-1,2,4-triazine