Uridine is white to off-white crystalline powder, while it's Molecular Formula is C9H12N2O6. white to off-white crystalline powder A nucleoside and one of main component in RNA.

What is the CAS number for Uridine?

The CAS number of Uridine is 58-96-8.

What is Uridine (58-96-8) used for?

Uridine is one of the four basic components of ribonucleic acid (RNA).InChI:InChI=1/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6+,7-,8-/m0/s1

Uridine is white to off-white crystalline powder, while it's Molecular Formula is C9H12N2O6. white to off-white crystalline powder A nucleoside and one of main component in RNA.

What is the CAS number for Uridine?

The CAS number of Uridine is 58-96-8.

What is Uridine (58-96-8) used for?

Uridine is one of the four basic components of ribonucleic acid (RNA).InChI:InChI=1/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6+,7-,8-/m0/s1

Uridine

Basic information

Product Name:Uridine
CasNo.:58-96-8
MF:C₉H₁₂N₂O₆

Physical and Chemical Properties

Purity:99%
Melting Point:163-167 °C(lit.)
Appearance:white to off-white crystalline powder

Inquiry

Product Details

CasNo： 58-96-8

MF： C₉H₁₂N₂O₆

Appearance： white to off-white crystalline powder

Buy Quality Uridine 58-96-8 In Stock with Immediately Delivery

Molecular Formula:C9H12N2O6
Molecular Weight:244.204
Appearance/Colour:white to off-white crystalline powder
Melting Point:163-167 °C(lit.)
Refractive Index:9 ° (C=2, H2O)
Boiling Point:387.12°C (rough estimate)
PKA:9.39±0.10(Predicted)
PSA：124.78000
Density:1.675 g/cm³
LogP:-2.85190

Uridine(Cas 58-96-8) Usage

Uridine is an important nucleoside that appears as a white crystalline powder. Uridine plays an important role in various physiological processes in the body, especially in nucleic acid metabolism and genetic information transmission. As a component of RNA, uridine is essential for gene expression and protein synthesis. It can be obtained by biological fermentation or chemical synthesis. In the medical field, uridine and its derivatives have potential applications in the treatment of certain neurological diseases and can be used as auxiliary components of anti-tumor drugs. For example, the mechanism by which uridine plays a role in the treatment of neurodegenerative diseases is a closely watched research topic.

InChI:InChI=1/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6+,7-,8-/m0/s1

58-96-8 Relevant articles

Circulating uridine dynamically and adaptively regulates food intake in humans

Ruth Hanssen,1,2,10 Lionel Rigoux,1,10 Kerstin Albus,3,4 Alina Chloé Kretschmer,1,2 Sharmili Edwin Thanarajah,1,5 Weiyi Chen,1,3 Yvonne Hinze,6 Patrick Giavalisco,6 Sophie M. Steculorum,1,3,9 Oliver A. Cornely,3,4,7,8

, Cell Rep Med. 2023 Jan 17;4(1):100897.

A study by Hanssen, Rigoux, et al. shows that, in humans, circulating uridine is a mediator of hunger and food intake that is dynamically regulated by caloric ingestion. Oral administration of uridine monophosphate (UMP) increases circulating uridine levels and can, under the right conditions, alter food behavior regulation.

Hydrolytic Reactions of the Diastereomeric Phosphoromonothioate Analogs of Uridyl(3',5')uridine: Kinetics and Mechanisms for Desulfurization, Phosphoester Hydrolysis, and Transesterification to the 2',5'-Isomers

Oivanen, Mikko,Ora, Mikko,Almer, Helena,Stroemberg, Roger,Loennberg, Harri

, p. 5620 - 5627 (1995)

Hydrolytic reactions of the RP and SP di...

Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

Owen S. Skinner, Joan Blanco-Fernández, Russell P. Goodman, Akinori Kawakami, Hongying Shen, Lajos V. Kemény, Lena Joesch-Cohen, Matthew G. Rees, Jennifer A. Roth, David E. Fisher, Vamsi K. Mootha & Alexis A. Jourdain

, Nature Metabolism volume 5, pages765–776 (2023)

While previous studies have shown that uridine can be salvaged to support pyrimidine synthesis in the setting of mitochondrial oxidative phosphorylation deficiency1, our work demonstrates that the ribose moiety of uridine or RNA can be salvaged to fulfil energy requirements via a pathway based on: (1) the phosphorylytic cleavage of uridine by uridine phosphorylase UPP1/UPP2...

58-96-8 Process route

: 1401327-14-7
2’-O-(2-cyano-2,2-dimethylethanimine-N-oxymethyl)uridine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7321-55-3
2,2-dimethylmalononitrile

: 58-96-8
uridine

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride; In dimethyl sulfoxide; at 25 ℃; for 0.25h;

5'-CGGCUXUUAACCGA-3', X=2-deoxouridine: 5'-CGGCUXUUAACCGA-3', X=2-deoxouridine

: 118-00-3
G

: 21052-20-0
1-(β-D-ribofuranosyl)-4-pyrimidinone

: 58-96-8
uridine

: 65-46-3
CYTIDINE

: 58-61-7
adenosine

Conditions

Conditions	Yield
5'-CGGCUXUUAACCGA-3', X=2-deoxouridine; With 1U P₁ nuclease; In aq. buffer; at 37 ℃; for 16h; pH=7; Enzymatic reaction; With 2U alkaline phosphatase; In aq. buffer; at 37 ℃; for 1h; Enzymatic reaction;

58-96-8 Upstream products

47791-58-2
C₁₈H₂₃N₅O₁₃P^(1-)
4105-38-8
2',3',5'-tri-O-acetyl-uridine
82913-19-7
[(2R,3R,4R)-3,4-diacetoxy-5-[2-oxo-4-(1,2,4-triazol-1-yl)pyrimidin-1-yl]tetrahydrofuran-2-yl]methyl acetate
4105-38-8
Tri-O-acetyluridine