What is the Monobenzone?

Monobenzone is cream to beige-light brownish crystals, while it's Molecular Formula is C13H12O2. cream to beige-light brownish crystals 4-Benzyloxyphenol is used in the synthesis of bis(4-benzyloxyphenoxy)phenyl phosphine oxide. It plays an essential role in the preparation of hetaryl-azophenol dyes via heterocyclic amines in nitrosyl sulphuric acid. It is also used for polyester fiber dyeing and in rubber industry. It acts as a depigmenting agent.

What is the CAS number for Monobenzone?

The CAS number of Monobenzone is 103-16-2.

What is Monobenzone (103-16-2) used for?

4-(Benzyloxy)phenol, also called monobenzone and monobenzyl ether of hydroquinone (MBEH) is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.InChI:InChI=1/C14H14O.C6H6O2/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14;7-5-1-2-6(8)4-3-5/h1-10H,11-12H2;1-4,7-8H

What is the Monobenzone?

Monobenzone is cream to beige-light brownish crystals, while it's Molecular Formula is C13H12O2. cream to beige-light brownish crystals 4-Benzyloxyphenol is used in the synthesis of bis(4-benzyloxyphenoxy)phenyl phosphine oxide. It plays an essential role in the preparation of hetaryl-azophenol dyes via heterocyclic amines in nitrosyl sulphuric acid. It is also used for polyester fiber dyeing and in rubber industry. It acts as a depigmenting agent.

What is the CAS number for Monobenzone?

The CAS number of Monobenzone is 103-16-2.

What is Monobenzone (103-16-2) used for?

4-(Benzyloxy)phenol, also called monobenzone and monobenzyl ether of hydroquinone (MBEH) is an organic chemical in the phenol family with chemical formula C6H5CH2OC6H4OH. It is used as a topical drug for medical depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans.InChI:InChI=1/C14H14O.C6H6O2/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14;7-5-1-2-6(8)4-3-5/h1-10H,11-12H2;1-4,7-8H

Monobenzone

Basic information

Product Name:Monobenzone
CasNo.:103-16-2
MF:C₁₃H₁₂O₂

Physical and Chemical Properties

Purity:99%
Melting Point:119-120 °C(lit.)
Appearance:cream to beige-light brownish crystals

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Product Details

CasNo： 103-16-2

MF： C₁₃H₁₂O₂

Appearance： cream to beige-light brownish crystals

99% Purity Commercial production Monobenzone 103-16-2 with Cheapest Price

Molecular Formula:C13H12O2
Molecular Weight:200.237
Appearance/Colour:cream to beige-light brownish crystals
Melting Point:119-120 °C(lit.)
Refractive Index:1.5906 (estimate)
Boiling Point:359.1 °C at 760 mmHg
PKA:10.29±0.15(Predicted)
Flash Point:213.4 °C
PSA：29.46000
Density:1.16 g/cm³
LogP:2.97120

Monobenzone(Cas 103-16-2) Usage

Monobenzone is a depigmenting agent. It is commonly used to treat skin hyperpigmentation conditions such as vitiligo. It achieves the depigmentation effect by destroying melanocytes and reducing the production of melanin in the skin. The use of monobenzone requires strict adherence to doctor's orders and specific usage methods, as improper use may lead to uneven depigmentation or other skin problems. It usually comes in the form of a cream or ointment and should be used with caution under the guidance of a doctor. For example, for some severe pigmentation diseases, monobenzone may be an effective treatment option, but the skin's reaction needs to be closely observed during use.

InChI:InChI=1/C14H14O.C6H6O2/c1-3-7-13(8-4-1)11-15-12-14-9-5-2-6-10-14;7-5-1-2-6(8)4-3-5/h1-10H,11-12H2;1-4,7-8H

103-16-2 Relevant articles

Expedient and simple method for regeneration of alcohols from toluenesulfonates using Mg-MeOH

Sridhar, Madabhushi,Kumar, B. Ashok,Narender

, p. 2847 - 2850 (1998)

Efficient conversion of toluenesulfonate...

Anti-Melanoma immunity and local regression of cutaneous metastases in melanoma patients treated with monobenzone and imiquimod; a phase 2 a trial

Hansje-Eva Teulings,Esther P. M. Tjin,Karina J. Willemsen,Stephanie van der Kleij,Sylvia ter Meulen,E. Helen Kemp,Gabrielle Krebbers,Carel J. M. van Noesel,Cornelis L. M. C. Franken,Jan W. Drijfhout,Cornelis J. M. Melief,Ludmila Nieuweboer-Krobotova,Omgo E. Nieweg,Jos A. van der Hage,J. P. Wietze van der Veen,Germaine N. RelyveldORCID Icon &Rosalie M. LuitenDept. of Dermatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Correspondence r.m.luiten@amc.uva.nl View further author information

, OncoImmunology Volume 7, 2018 - Issue 4

We investigated a novel immunotherapeutic approach of the skin-depigmenting compound monobenzone synergizing with imiquimod in inducing antimelanoma immunity and melanoma regression. Stage III-IV melanoma patients with non-resectable cutaneous melanoma metastases were treated with monobenzone and imiquimod (MI) therapy applied locally to cutaneous metastases and adjacent skin during 12 weeks, or longer.