What is the Glycyrrhizic acid?

Glycyrrhizic acid is White powder, while it's Molecular Formula is C42H62O16. White powder Glycyrrhizic acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.

What is the CAS number for Glycyrrhizic acid?

The CAS number of Glycyrrhizic acid is 1405-86-3.

What is Glycyrrhizic acid (1405-86-3) used for?

Glycyrrhizic acid is a kind of anti-inflammatory triterpene glycoside extracted from the licorice root. Inside the body, it can be metabolized to glycyrrhetinic acid which inhibits the 11-beta-hydroxysteroid dehydrogenase and some other enzymes related to the corticosteroid metabolism. Glycyrrhizic acid has various pharmacological effects including suppressing hepatic apoptosis and necrosis, anti-inflammatory and immune regulatory actions, antiviral effects, antineoplastic and anticancer effects. It is the active ingredient of licorice root which is commonly used in the treatment of acute and chronic liver injury, viral hepatitis, hepatic steatosis, liver fibrosis, hepatoma, viral myocarditis and other diseases such as psoriasis or prostate cancer. Glycyrrhizic acid is also widely used as a sweetening and flavoring agent in food.InChI:InChI=1/C41H60O16.3H3N/c1-37(2)21-8-11-40(5)18-7-10-38(3)13-14-39(4,36(52)53)16-19(38)17(18)15-20(42)31(40)41(21,6)12-9-22(37)54-34-27(47)25(45)28(30(57-34)33(50)51)55-35-26(46)23(43)24(44)29(56-35)32(48)49;;;/h15,18-19,21-31,34-35,43-47H,7-14,16H2,1-6H3,(H,48,49)(H,50,51)(H,52,53);3*1H3/t18?,19-,21?,22-,23-,24-,25+,26+,27+,28-,29-,30-,31?,34+,35+,38-,39-,40-,41-;;;/m0.../s1

What is the Glycyrrhizic acid?

Glycyrrhizic acid is White powder, while it's Molecular Formula is C42H62O16. White powder Glycyrrhizic acid is a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.

What is the CAS number for Glycyrrhizic acid?

The CAS number of Glycyrrhizic acid is 1405-86-3.

What is Glycyrrhizic acid (1405-86-3) used for?

Glycyrrhizic acid is a kind of anti-inflammatory triterpene glycoside extracted from the licorice root. Inside the body, it can be metabolized to glycyrrhetinic acid which inhibits the 11-beta-hydroxysteroid dehydrogenase and some other enzymes related to the corticosteroid metabolism. Glycyrrhizic acid has various pharmacological effects including suppressing hepatic apoptosis and necrosis, anti-inflammatory and immune regulatory actions, antiviral effects, antineoplastic and anticancer effects. It is the active ingredient of licorice root which is commonly used in the treatment of acute and chronic liver injury, viral hepatitis, hepatic steatosis, liver fibrosis, hepatoma, viral myocarditis and other diseases such as psoriasis or prostate cancer. Glycyrrhizic acid is also widely used as a sweetening and flavoring agent in food.InChI:InChI=1/C41H60O16.3H3N/c1-37(2)21-8-11-40(5)18-7-10-38(3)13-14-39(4,36(52)53)16-19(38)17(18)15-20(42)31(40)41(21,6)12-9-22(37)54-34-27(47)25(45)28(30(57-34)33(50)51)55-35-26(46)23(43)24(44)29(56-35)32(48)49;;;/h15,18-19,21-31,34-35,43-47H,7-14,16H2,1-6H3,(H,48,49)(H,50,51)(H,52,53);3*1H3/t18?,19-,21?,22-,23-,24-,25+,26+,27+,28-,29-,30-,31?,34+,35+,38-,39-,40-,41-;;;/m0.../s1

Glycyrrhizic acid

Basic information

Product Name:Glycyrrhizic acid
CasNo.:1405-86-3
MF:C₄₂H₆₂O₁₆

Physical and Chemical Properties

Purity:99%
Melting Point:220ºC decomposes
Appearance:White powder

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Product Details

CasNo： 1405-86-3

MF： C₄₂H₆₂O₁₆

Appearance： White powder

Perfect Factory Offer Excellent quality Glycyrrhizic acid 1405-86-3 with Safe Shipping

Molecular Formula:C42H62O16
Molecular Weight:822.945
Appearance/Colour:White powder
Vapor Pressure:0mmHg at 25°C
Melting Point:220ºC decomposes
Refractive Index:61 ° (C=1.5, EtOH)
Boiling Point:971.4 °C at 760 mmHg
PKA:2.76±0.70(Predicted)
Flash Point:288.1 °C
PSA：267.04000
Density:1.43 g/cm³
LogP:2.24560

Glycyrrhizic acid(Cas 1405-86-3) Usage

Definition	ChEBI: A triterpenoid saponin that is the glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.
Safety Profile	Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by ingestion: somnolence and changes in the metabolism of phosphorus, When heated to decomposition it emits acrid smoke and irritating fumes.

InChI:InChI=1/C41H60O16.3H3N/c1-37(2)21-8-11-40(5)18-7-10-38(3)13-14-39(4,36(52)53)16-19(38)17(18)15-20(42)31(40)41(21,6)12-9-22(37)54-34-27(47)25(45)28(30(57-34)33(50)51)55-35-26(46)23(43)24(44)29(56-35)32(48)49;;;/h15,18-19,21-31,34-35,43-47H,7-14,16H2,1-6H3,(H,48,49)(H,50,51)(H,52,53);3*1H3/t18?,19-,21?,22-,23-,24-,25+,26+,27+,28-,29-,30-,31?,34+,35+,38-,39-,40-,41-;;;/m0.../s1

1405-86-3 Relevant articles

Syntheses of glycyrrhetic acid α-diglycosides and enol α-glycosides

Saito,Sumita,Kanda,Sasaki

, p. 1016 - 1027 (1994)

Glycyrrhetinate α-monoglycoside derivati...

A method for the preparation of trans-glycyrrhizic acid

-

Paragraph 0018; 0021; 0024, (2019/07/04)

The invention takes the market glycyrrhi...

METHOD FOR PRODUCING GLYCYRRHIZINIC ACID AND GALACTURO GLYCYRRHIZINIC ACID, AND INTERMEDIATE USED FOR THE PRODUCTION METHOD

-

Paragraph 0039; 0045, (2018/07/28)

PROBLEM TO BE SOLVED: To provide a synth...

Methyl isoglycyrrhizinate refining method

-

Paragraph 0016, (2018/04/02)

According to the present invention, a me...

Acyclovir transdermal delivery system

-

, (2008/06/13)

A transdermal formulation for providing ...

1405-86-3 Process route

: diammonium glycyrrhizinate

: 1405-86-3
glycyrrhizin

: 18α-glycyrrhizic acid

Conditions

Conditions	Yield
With sulfuric acid; In methanol; at 0 ℃; pH=3; Overall yield = 98 g;	56.25 % de

: C₄₅H₆₈O₁₅

: 1405-86-3
glycyrrhizin

Conditions

Conditions	Yield
With sodium hydroxide; for 2h; Reflux;	8.5 g

1405-86-3 Upstream products

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2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl-11-oxoolean-12-en-30-oate